Vitamin D & Inflammation Test
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Our at-home lab test can help you understand if you're maintaining an adequate vitamin D level and check for acute inflammation that may be causing discomfort.
Measures 25-OH D and hsCRP
Finger prick sample
We measure your vitamin D (25-OH D) and high-sensitivity C-reactive protein (hs-CRP) levels.
Your results will show your levels of high-sensitivity CRP (hsCRP) and vitamin D and can help you identify lifestyle modifications that support healthy levels of these two biomarkers.
Vitamin DVitamin D has many important roles in the body, including bone formation and maintenance as well as immune function, among others. It forms in the body when the sun is absorbed by your skin and is found in natural and fortified food sources. Low intake levels of vitamin D over time may lead to a vitamin D deficiency.
hs-CRPhs-CRP, or high-sensitivity C-reactive protein, is a non-specific, acute-phase protein that the liver makes in response to inflammation in the body. It may be elevated due to certain chronic illnesses, medications, or recent illnesses. hs-CRP level can be used in the clinical setting as part of a broader, comprehensive assessment evaluating heart health.
Vitamin D helps the body use calcium and is essential for strong bones, but if your body is deficient, you may experience higher levels of inflammation and a variety of other symptoms like:
- Weakness
- Joint pain
- Muscle pain
- Fatigue or feeling tired
At-home lab testing made easy
- Pre-paid shipping (both ways)
- Everything you need to collect your sample and send it in
- Detailed directions and an instructional video
- Our care team is standing by if you have questions
- Digital (and printable) results
- Educational video sessions, led by healthcare professionals
- View sample collection video

Vitamin D & Inflammation Test
Free shipping
FSA / HSA accepted
Better health starts here
How it all works
1
Register your test
Once your test arrives, head to everlywell.com or open your Everlywell app to register. Just Scan the QR code on the box to seamlessly plug in your test ID.


2
Test from the comfort of home
When you're ready, collect your sample and mail it in (following the directions in your kit) using the prepaid shipping label.


3
Get answers in days
Your physician-reviewed results will be ready in your account in a few days.


4
Healthy doesn’t happen alone
We'll offer lifestyle insights and guidance tailored to your results that you can use to make healthier choices.


1
Register your test
Once your test arrives, head to everlywell.com or open your Everlywell app to register. Just Scan the QR code on the box to seamlessly plug in your test ID.


2
Test from the comfort of home
When you're ready, collect your sample and mail it in (following the directions in your kit) using the prepaid shipping label.


3
Get answers in days
Your physician-reviewed results will be ready in your account in a few days.


4
Healthy doesn’t happen alone
We'll offer lifestyle insights and guidance tailored to your results that you can use to make healthier choices.



100% digital
Your results
Easy to access, even easier to understand
Gain meaningful insights about your health with easy-to-understand test results without the complex jargon.
You'll receive a complete breakdown of your report—including each marker tested and what your results mean for you.
Use your report to make an action plan with concrete next steps. And don't worry, we'll provide some additional resources and helpful tips along the way.
Care you can count on
Backed by science, reviewed by doctors

CLIA-certified laboratories
Each lab we work with is CLIA-certified (Clinical Laboratory Improvement Amendments). This means they must meet high standards to obtain both state and federal certifications and submit themselves to regular inspections.

Physician-reviewed results
All tests are reviewed by an independent board-certified physician within your state.

Your privacy matters
Everlywell is HIPAA-compliant. This means we never sell your health data and we always store it securely—in fact, we use state-of-the-art, bank-grade encryption.
Reviews
98%
Would recommend this test to a friend
4.8 out of 5
5 star
85%
4 star
12%
3 star
2%
2 star
0%
1 star
1%
Review Snapshot
by PowerReviews
Ratings Distribution
5 Stars
334
4 Stars
46
3 Stars
7
2 Stars
0
1 Star
4
Pros
- No Pros
Cons
- No Cons
Most Liked Positive Review
Too slow compared to competition
It was easy enough. I have used other online labs and just could not get over having to wait 2 weeks, when I'm used to getting my results to them in one day and results back in 2. If you have a doctor appointment and wish to discuss your results, please, give yourself 3 weeks to be safe if using thi...s company. I have NOTHING bad to say, at all, except using USPS snail mail???? for lab results. I referred 3 friends and they all are still waiting on their results, we all bought around the 1st of the year. So holiday shipping was over. The results and explanation report was formal. I enjoyed everything. I became a member, as did my friends, however I got nothing for referring them and they are dumping the membership to go with a random test if ever needed. It's the wait time, it's rediculous. This is medical. One week turn around is acceptable. I'm used to 4 day turn around with the competition. So I cancelled my doc appointment and had to reschedule. I will not recommend, because I feel like I shouldn't have had to read the fine print when referring so many people. I thought convincing them to become members would be of more value to the company, they should have just bought a test and not become members Because they to thought by referring they would get the hyped referral promotion. So they're all upset as well. I will only recommend to a friend who has all the time in the world and doesn't need results back for any other reason but for personal knowledge. It's just way to slow. And I feel burnt by the companies referral program. I did find out that I have astronomical inflammation, 2 weeks later, and I'm told to do another test within 2 weeks. That's not possible with this company. But it is with the company I have been using for a year now. Everlywell was new to me so to see a USPS label when I went to send off, I knew then. This was only going to be good for those things that you just might be curious about. But for sure nothing that is of great medical concern
Most Liked Negative Review
It Works
As advertised, I received the results. They are general in nature, with little detail. The Vitamin D test showed low at 21. Other input is that 21 is in the general range of good. So, some confusion. Would like to have followup after taking Vitamin D supplements for a few months to see if it in...creases and by how much.
Reviewed by 391 customers
Great
Submitted 1 year ago
By layna
From Usa
Verified Buyer
Great product!
Merchant Response
Thank you for choosing Everlywell, Layna! 💚
I highly recommend this test
Submitted 1 year ago
By Marie
From Illinois
Verified Buyer
Easy to do and quick results!
Merchant Response
Thank you for your review, Marie! We're happy to hear that you enjoyed your at-home testing experience.
Great source of tests
Submitted 1 year ago
By Laura
From Santa Clarita
Verified Buyer
This was so helpful to know my test results between my regular yearly panel. They actually turned out to be good results which helped remove some stress. The testing and sending it off in the mail was easy.
Merchant Response
Thank you for your review, Laura! We're so glad to hear that you enjoyed the ease and peace of mind of at-home testing with Everlywell.
I would buy again
Submitted 1 year ago
By Yvette
From Issaquah
Verified Buyer
The test was easy to use.
Merchant Response
Thank you for choosing Everlywell for your at-home testing needs, Yvette! 💚
Yes
Submitted 1 year ago
By BK
From Los Angeles
Verified Buyer
The paper blood collection is difficult and troubleson. The newer cassette is far superior and convenient.
Merchant Response
Thank you for your feedback, BK! While our Vitamin D & Inflammation Test currently utilizes a dried blood spot collection, we're happy to hear that you're enjoying the collection cassette method for several of our other test kits. We'll be sure to pass this feedback along to our team!
Recommend this to see how inflamed you are
Submitted 1 year ago
By Eightball
From Semmes, AL
Verified Buyer
I love that Everlywell does not use LabCorp for processing lab work. I'm glad there was a second lancet because I ended up needing it after all. It's easy to use. I've had chronic inflammation for almost 7 years. I was curious to see where my vitamin D level was and how much inflammation I had at that present moment. I feel like it was pretty accurate. In 2021, a coworker recommended I take the food sensitivity test and I did and found out which foods to eliminate and then slowly reintroduce to my diet. There were several that were causing inflammation at the time.
Merchant Response
Thank you for your review, Eightball! We appreciate you sharing your experience with us, and we're so happy to hear that you've gained helpful insight from your test results. Please note that while IgG reactivity (measured by our Food Sensitivity Test) can be viewed as a form of inflammation, is not clinically interpreted as such. Other biomarkers, such as hs-CRP (measured by our Vitamin D & Inflammation Test), are more commonly used to evaluate levels of inflammation in the body. If you have any questions, please reach out to our Customer Experience Team for support!
Review
Submitted 1 year ago
By Jesse
From New Orleans
Verified Buyer
5 star
The Vitamin D & inflammation Test have worked well for me.
Submitted 1 year ago
By Ami
From Oregon
Verified Buyer
These kits are so handy for patients who have a hard time traveling.
I would buy this product (or other home tests) again
Submitted 1 year ago
By Joy
From Raleigh, NC
Verified Buyer
Very user friendly, easy to follow directions, good communication regarding kit status (shipping/delivery/results)
yes
Submitted 1 year ago
By bill
From texas
Verified Buyer
very good service.
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FAQs
You have questions, we have answers
Inflammation is the body’s immune response to an irritant. The irritant could be trauma from an injury, chemicals, or an infection. The body responds with pain, swelling, and redness, which are all part of the initial inflammatory response.
Short-term inflammation is referred to as acute inflammation and is usually self-limiting. Acute inflammation is often a sign your body is working to fight an infection or heal itself. In contrast, when inflammation persists, or is in response to the body's own cells, it is referred to as chronic inflammation. In chronic inflammation, your body’s immune system continues to send out its main defenders, white blood cells, and other messengers to fight. Sometimes these defenders can end up attacking nearby healthy tissues or cells. This immune system response can persist for prolonged periods of time or even indefinitely. Our inflammatory marker test measures your body’s level of a protein whose levels are elevated when inflammation is present (acute or chronic).
Chronic inflammation has been implicated in a wide variety of disorders, including:
Heart disease
Diabetes
Dementia
Alzheimer's disease
Lupus
Crohn's disease
Cancer
C-reactive protein, or CRP, is a protein that increases in the blood with inflammation. The high-sensitivity CRP blood test (hs-CRP) can detect even small elevations of CRP protein as an indicator of low levels of inflammation in the body.
You might consider this inflammation test if you’re experiencing any of the symptoms listed below.
Symptoms of chronic inflammation are often vague and may go undetected, but can include:
Ongoing, Irritating Pain in Joints or Muscles
Constant Fatigue or Lethargy
Frequent Infection
Gastrointestinal complications like constipation, diarrhea, and reflux
Insomnia
Vitamin D is widely known to be essential for strong bones as it helps the body use calcium, but if you are deficient, there are a wide variety of other symptoms one can experience:
Excessive Sweating
Noticeable and Unexpected Weakness
Broken Bones
Chronic Pain
Depression
Fatigue
Related test for fatigue symptoms: Thyroid Test
Your results from our high-sensitivity CRP test will contain your levels of CRP and vitamin D and whether they are low, normal, or high compared to the appropriate reference ranges.
It is important to understand that a single C-reactive protein (CRP) level does not tell the complete story. High-sensitivity CRP levels can be temporarily elevated by your body’s response to a recent illness, bacterial infection, or trauma. A high CRP level should be confirmed with follow-up testing. To identify signs of chronic inflammation, a healthcare provider may test for additional markers of inflammation.
Everlywell can suggest dietary and lifestyle changes that can help you regulate vitamin D levels in your body.
If your vitamin D levels are low, you may wish to modify your diet and sunlight exposure to maximize vitamin D levels in your body.
If you exhibit elevated CRP levels, you may consider waiting a month or so and retesting, as the high CRP levels might be the result of recent illness, infection, or trauma.
Once you get your results back from our inflammation level test (CRP testing), you can then show them to your healthcare provider and discuss potential next steps. Sharing your Everlywell results with your doctor is the best way to create informed decisions about your health and wellness planning.
Low vitamin D levels can result in vitamin D deficiency. Vitamin D deficiency can lead to symptoms like fatigue, depression, and joint pain—and more. In addition, a low vitamin D level may also be linked to serious health conditions like heart disease and bone weakness (in the form of osteomalacia).
The main cause of vitamin D insufficiency is a lack of sun exposure. That’s because your body makes vitamin D when your skin comes into contact with sunlight. Dietary vitamin D sources are few and far between, so sunlight is actually the body’s main source of vitamin D. Fortunately, an at-home vitamin deficiency test that checks vitamin D levels can help you find out if you’re getting enough of this key nutrient.
Risk factors for vitamin D deficiency include the following:
History of gastric bypass surgery
Dairy allergies
Lactose intolerance
Vegan or ovo-vegetarian diets
Fat malabsorption conditions, such as celiac disease, ulcerative colitis, and Crohn's disease
Healthcare providers often prescribe a high-dose vitamin D supplement to help reverse vitamin D deficiencies as quickly as possible. However, because too much vitamin D supplementation can result in toxicity, be sure you talk to your healthcare provider before taking high doses of vitamin D, or any other alterations to your diet or supplement routines.
Learn more about vitamin D deficiency: Vitamin D Deficiency Symptoms
Too much vitamin D supplementation can result in vitamin D toxicity—meaning your body doesn’t have optimal vitamin D levels because it’s actually getting too much vitamin D. Toxicity is the opposite of a vitamin D deficiency and is linked with excess calcium absorption (which can lead to a condition known as hypercalcemia).
Fortunately, frequent sun exposure will not lead to vitamin D toxicity because sunlight breaks down any extra vitamin D in your skin.
Common symptoms of vitamin D toxicity include:
Kidney stones
Anorexia
Diarrhea, constipation, nausea, and vomiting
Bone pain
Frequent urination
Drowsiness
Constant headaches
Irregular heartbeat
It's always a good idea to talk to your healthcare provider about your supplement routines, especially if you plan on changing them.
The Everlywell Vitamin D and Inflammation Test is an easy way to check your vitamin D and hs-CRP levels. Here’s how it works:
Once you order the Vitamin D Test kit (do that by clicking the “Add to Cart” button and completing checkout), we’ll ship it directly to you.
Register your test online at www.everlywell.com/register using the unique kit ID that’s included in your kit.
To take this blood test, use the card inside the kit to collect your blood sample. The kit includes a lancet for pricking your finger and simple instructions to guide you through the process.
Once you’ve completed collection, ship your sample to a lab using the prepaid shipping label in the kit.
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